0
Search

BA4F04 Blood Clotting Cascade Affected by Warfarin Level 4

INTRODUCTION

Blood in the body needs to flow continuously and smoothly throughout the body for an entire lifetime in order to keep the body fit and fine. Blood clots can help in preventing excessive blood from the body. But blood clots in critical areas such as brain or heart can give life threatening damage to body. To prevent blood clots, Warfarin has been prescribed by the doctor. It has some sort of side effects that can influence the body system. To prevent those side effects it has to keep in homeostatic range. Uncontrolled blood pressure, Stomach ulcers, gastritis, cancers are some effects which can be observed after Warfarin dosage.

ASSIGNMENT HELP AU We Aim At:
  • Offering the best assignment writing help
  • Delivering the orders as fast as possible
  • Providing maximum satisfaction at affordable rates
Call Now : +61 363612345

Body

Blood clots are health and lifesaving when they stop bleeding. But they can also form when they aren't needed and cause a heart attack, stroke, or other serious medical problems. To prevent blood clots in lethal areas, Warfarin has been prescribed by the health care professionals (Sekhri and et.al., 2016). The medicine possesses some side effects which can impact on body negatively. Warfarin is an antagonist for Vitamin K and can only be administered orally. It blocks the functions of vitamin K dependent clotting factors (II, VII, IX, X) (Leite, Martins and Castilho, 2016). The goal of warfarin therapy is to minimise the blood clots in critical areas. It is important to monitor the effect of warfarin carefully with blood testing. In order to maintain homeostasis, the endocrine system of body plays crucial role. As hormones regulate the activity of body cells, the endocrine system of body helps in maintaining homeostasis. The clotting Factors (II, VII, IX, X) has been identified due to Warfarin (Graham and et.al., 2015). The name of these factors are described below in the table:

Factors

Name

II

Prothrombin

VII

Proconvertin/Stable Factor

IX

Plasma Thromboplastin component

X

Stuart Prower Factor

Clotting can occur through two different pathways which are intrinsic pathway and extrinsic pathway. Due to internal bleeding, clotting can occur through intrinsic pathway and due to release in tissue factors due to physical injury clotting occur through extrinsic pathway (Bouchnita and et.al., 2016).

From the above image it can be understood that the suppression of the Factors II (Prothrombin), VII, IX and X have an effect on the establishment of a stable fibrin clot. There is direct effect of extrinsic pathway due to suppression of Factor VII (Siegmund and et.al., 2016). By suppressing the factor the whole pathway can be blocked. Intrinsic pathway can be affected due to inhibition of Factor IX and X. Factor X has a double effect on the extrinsic pathway because if there is still some factor VII in the blood stream it will have no factor X to react with. Thus, it is essential for the health care professionals to monitor the effect of warfarin in patient through blood testing effectively.

You may also like to read: 

 

REFERENCES

  • Bouchnita, A., Bouzaachane, K., Galochkina, T., Kurbatova, P., Nony, P., & Volpert, V. (2016). An individualized blood coagulation model to predict INR therapeutic range during warfarin treatment.Mathematical Modelling of Natural Phenomena,11(6), 28-44.
  • Graham, E. J., Hood, K., Ma, Y., Radunskaya, A., & Simons, J. (2015). Injury-initiated clot formation under flow: a mathematical model with warfarin treatment. InApplications of Dynamical Systems in Biology and Medicine(pp. 75-98). Springer, New York, NY.
  • Holland, G. C. (2016).The Effect of Acute Exercise on Coagulation Factors and the Mechanical Properties of Fibrin Fibers(Doctoral dissertation, Wake Forest University).
  • Leite, P. M., Martins, M. A. P., & Castilho, R. O. (2016). Review on mechanisms and interactions in concomitant use of herbs and warfarin therapy.Biomedicine & Pharmacotherapy,83, 14-21.
  • Sekhri, A., Lisinschi, A., Furqan, M., Palaniswamy, C., Mukhi, N., Gupta, R., & Nelson, J. C. (2016). The Conundrum of “Warfarin Hypersensitivity”: Prolonged Partial Thromboplastin Time From Factor IX Propeptide Mutation.American journal of therapeutics,23(3), e911-e915.
  • Siegmund, H. U., Burghaus, R., Kubitza, D., & Coboeken, K. (2015). Contribution of rivaroxaban to the international normalized ratio when switching to warfarin for anticoagulation as determined by simulation studies.British journal of clinical pharmacology,79(6), 959-966.

You may also like to read: 

Download Full Sample
Cite This Work To export references to this Sample, select the desired referencing style below:
Copy to Clipboard copy icon
Copy to Clipboard copy icon
Copy to Clipboard copy icon
Copy to Clipboard copy icon
Instant Assignment Help. [Internet]. Instant Assignment Help.(2022), Retrieved from: https://www.instantassignmenthelp.com.au/free-samples/health/ba4f04-blood-clotting-cascade-affected-by-warfarin-level-4
Copy to Clipboard copy icon

Writing a financial accounting assignment is no easy feat. Students should have in-depth knowledge about every concept and formula related to accounting and finance to excel in assignments. Those who lack knowledge seek accounting assignment help from us. We also provide cost accounting assignment writing help as our writers carry years of experience and are well-versed with the subject’s concepts. You can reach us anytime for corporate accounting assignment help and be assured of getting high-quality work that is worth an A+.

Boost Grades & Leave Stress

Share Your Requirements Now for Customized Solutions.

Lowest Price
USD6

Delivered on-time or your money back

100+ Qualified Writers

For Best Health Assignment Help

  • expert name
    2544 Completed Orders
    Robin StuartView Profile Hire Me
  • expert name
    1235 Completed Orders
    Jim CrugusView Profile Hire Me
  • expert name
    965 Completed Orders
    Samara JamesView Profile Hire Me
  • expert name
    1363 Completed Orders
    Miley SteveView Profile Hire Me
  • FREE Tools

    To Make Your Work Original

    Our Unique Features

    24/7 Customer Support

    100% Customer Satisfaction

    No Privacy Infringement

    Quick Services

    Subject Experts

    Innovative Documents

    Don't Miss Our Special Offers